Posts Tagged ‘micro organisms’

Identification of the causal organism

This may be made by methods of direct diagnosis including demonstration of the organism microscopically in preparations of tissue, exudate or excreta, isolation of the organism in laboratory culture or, more rarely, its growth in laboratory animals. In cases where these methods are inapplicable or unavailing, methods of indirect diagnosis must be used to demonstrate the presence of specific antibody in the patient’s serum. The significance of the isolation of certain micro-organisms may require further support by the demonstration of homologous antibody, e.g. the mere isolation of an enterovirus from the faeces may be equivocal without an accompanying significant rise in corresponding antibody titre