MORE COMPLEX INFLAMMATORY RESPONSES
However, these patterns of cellular responses can also be ‘turned against us’ in various diseases if they occur inappropriately or in a uncontrolled fashion. For example, an excessive or inappropriate acute inflammatory response is responsible for many acute tissue injury syndromes, acute goat and acute glomerulonephritis. A chronic inflammatory response and chronic tissue destruction or an excessive fibrogenic response are key features of reheumatoid arthritis, chronic pyelonephritis, fibrosing alveolitis and chronic bronchitis and emphysema. An allergic inflammatory response characterizes asthma and eczema. The vast redundancy of mechanisms displayed in various aspects of the inflammatory response may be advantageous in antibacterial host defense but it poses problems for the development of specific therapy in inflammatory diseases.